2019 Update of the Joint European League Against Rheumatism and European Renal Association–European Dialysis and Transplant Association (eular/era–edta) recommendations for the management of lupus nephritis



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6.2 At each visit, body weight, blood pressure (including out- of- office measures), estimated GFR, serum albumin, proteinuria (UPCR or 
24 hours urine collection), urine red cell count or sediment and complete blood cell count should be evaluated when nephritis is active and 
less frequently if stable.
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Serum C3/C4 and anti- dsDNA antibody levels are monitored periodically.
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6.3 Repeat kidney biopsy should be considered in selected cases, such as worsening of kidney variables, non- responsiveness to 
immunosuppressive or biologic treatment (as defined above); or at relapse, to demonstrate possible histologic class transition or change 
in chronicity and activity indices; to provide prognostic information; and detect other pathologies.

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